6/25/2023 0 Comments Does taurine give you energySodium and chloride move into cells by means of an external to internal downhill Na + gradient (a chemical gradient), and then the sodium is pumped out of the cell by Na +K +-dependent ATPase. The model that best describes this transport is 2 Na +:1 taurine:1 Cl - (Figure 1). In addition to sodium, taurine uptake by renal epithelia requires chloride or bromide. The active uphill transport of taurine occurs via a sodium-dependent transporter (TauT). Some of these properties lead to the role of conjugation of bile acids and uridine in tRNA. It has the lowest pK 1 and pK 2 of all amino acids. Its accumulation within the cell requires active transport from the extracellular environment, where it is found in only micromolar quantities. The taurine molecule acts as a zwitterion at physiologic pH and resides within the cell in millimolar quantities. Taurine is not incorporated into protein, and can serve as an intracellular osmolyte. It is readily soluble in aqueous solutions. The physiochemical properties of the ß-amino acid taurine are probably responsible for some of its biologic characteristics. In addition, the role of taurine in the pathophysiology of kidney disease will be examined. Thus, this review will focus on several aspects of renal function in relation to taurine and will cover large biologic themes. The numerous physiologic regulators of taurine handling by the kidney have been recently reviewed. Taurine participates in several biologic processes in the kidney, and the kidney influences specific aspects of taurine homeostasis. The interactions between the kidney and taurine are many and varied.
0 Comments
Leave a Reply. |